Neurology· Topic 10.12 Trauma, motor neuron disease, and other neurologic disorders· 10.12.11

Chronic subdural hematoma

A collection of liquefied blood between the dura and arachnoid that develops over weeks after often-trivial or forgotten trauma, typically in elderly or anticoagulated patients with cerebral atrophy; CT confirms the diagnosis, and burr-hole drainage is the treatment for a symptomatic hematoma with significant thickness or midline shift.

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What this article covers

  • Overview

    Definition: chronic subdural hematoma (cSDH) is a collection of liquefied, often membrane-encapsulated blood in the subdural space (between the dura mater and arachnoid) that develops days to weeks…

  • Epidemiology

    Predominantly a disease of older adults, reflecting the age-related cerebral atrophy that predisposes to bridging vein rupture from even minor trauma.

  • Risk factors

    Advanced age: cerebral atrophy increases the subdural space and tension on bridging veins, the central predisposing mechanism.

  • Pathophysiology

    Bridging vein rupture: trauma, even minor, shears the bridging veins that cross the subdural space from the cortical surface to the dural venous sinuses; in an atrophic brain these veins are already…

  • Clinical features

    Nonspecific presentation: headache, altered mental status, or somnolence are the most common findings, often mistaken initially for dementia, stroke, or a metabolic disturbance in an older patient.

  • Differential diagnosis

    Acute subdural hematoma: presents with coma or rapid neurologic compromise within hours of major trauma, versus the gradual, weeks-long evolution after trivial or forgotten trauma seen in chronic subdural hematoma.

  • Diagnosis

    Establishing the diagnosis: noncontrast head CT showing a crescent-shaped extra-axial collection along the cerebral convexity that is hypodense (older blood) or of mixed/isodense density (recent…

  • Management

    First step: reverse any anticoagulation or coagulopathy urgently once the diagnosis is made and before proceeding to intervention, using the specific reversal agent for the anticoagulant involved…

  • Complications

    Recurrence: chronic subdural hematoma recurs after drainage in a meaningful minority of patients, particularly with incomplete evacuation, ongoing anticoagulation, or a persistent membrane.

  • Prognosis

    Generally favorable with timely drainage: most patients who undergo burr-hole evacuation for a symptomatic hematoma show substantial clinical improvement.

  • Prevention

    Fall-risk reduction in older adults: annual fall-risk screening in adults age 65 and older, with home safety assessment, gait and balance evaluation, and treatment of contributing factors…

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