Gastroenterology· Topic 5.5 Colonic and anorectal disease· 5.5.6

Diverticular bleeding

Diverticular bleeding is painless arterial hematochezia from rupture of a vasa recta at the neck or dome of a colonic diverticulum, the most common cause of severe acute lower gastrointestinal bleeding, and it stops spontaneously in about 75% of episodes. Diagnosis rests on hemodynamic triage followed by urgent colonoscopy or CT angiography to localize the source, and management combines resuscitation with a restrictive transfusion threshold, endoscopic hemostasis, and angiographic embolization or surgery for refractory bleeding.

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What this article covers

  • Overview

    Definition: diverticular bleeding is acute, painless hematochezia caused by rupture of a vasa recta, the small penetrating artery crossing the dome or neck of a colonic diverticulum.

  • Epidemiology

    Built on a common substrate: diverticulosis is present in roughly 80% of people 85 years and older, and about 15% of patients with diverticulosis develop a complication, chiefly bleeding or diverticulitis.

  • Risk factors

    Diverticulosis itself: the obligate substrate; bleeding cannot occur without an existing diverticulum.

  • Pathophysiology

    Diverticulum formation: chronic elevation of intraluminal colonic pressure combined with focal weakness of the colonic wall produces herniation of mucosa and submucosa through the muscularis at the…

  • Clinical features

    Sudden, painless hematochezia: the hallmark presentation is the abrupt passage of maroon or bright red blood per rectum without preceding or accompanying abdominal pain, which is the key feature…

  • Differential diagnosis

    Diverticulitis: left lower quadrant pain, fever, and leukocytosis from peridiverticular inflammation; rectal bleeding is uncommon, unlike the painless hemorrhage of diverticular bleeding (Diverticulitis).

  • Diagnosis

    Diverticular bleeding is confirmed by direct visualization of active bleeding, a nonbleeding visible vessel, or an adherent clot at a diverticulum on colonoscopy, or by extravasation from a…

  • Management

    Resuscitate first, in parallel with localization: two large-bore (minimum 18-gauge) peripheral IV catheters, IV crystalloid to restore hemodynamic stability, correction of coagulopathy, and…

  • Complications

    Hemorrhagic shock: occurs with brisk, ongoing bleeding before stabilization and source control are achieved.

  • Prognosis

    Favorable in the majority: about 75% of episodes stop spontaneously, and most patients recover fully with or without endoscopic intervention.

  • Prevention

    Avoid nonaspirin NSAIDs indefinitely after any episode of diverticular or angiodysplasia-related bleeding.

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