Neurology· Topic 10.6 Cranial neuropathy, vertigo, and balance disorders· 10.6.1

Facial palsy

Facial palsy is weakness of the muscles innervated by the facial nerve (cranial nerve VII); most cases are idiopathic (Bell palsy), producing unilateral weakness of both upper and lower facial muscles, distinguishing it from the upper-face-sparing pattern of a central (stroke) lesion. Classic Bell palsy needs no imaging and is treated with a 10-day course of oral prednisone started within 72 hours of onset.

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What this article covers

  • Overview

    Definition: facial palsy is weakness or paralysis of the muscles of facial expression resulting from dysfunction of the facial nerve (cranial nerve VII) or its central pathways.

  • Epidemiology

    Common condition: peripheral facial palsy, predominantly Bell palsy, is a frequently encountered cranial neuropathy in outpatient and emergency settings.

  • Risk factors

    Pregnancy: increased incidence in the third trimester and immediate postpartum period.

  • Pathophysiology

    Presumed viral/inflammatory mechanism in Bell palsy: the leading hypothesis is reactivation of latent herpes simplex virus within the geniculate ganglion, producing inflammation and edema of the…

  • Clinical features

    Diagnostic pattern for classic Bell palsy: acute (hours to 1-2 days) unilateral facial weakness involving both the upper face (impaired forehead wrinkling, incomplete eye closure) and lower face…

  • Differential diagnosis

    Central facial weakness (stroke or other upper motor neuron lesion): spares the forehead and eye closure from bilateral cortical innervation, and is often accompanied by contralateral limb weakness…

  • Diagnosis

    Bell palsy is a clinical diagnosis of exclusion: established by the acute, unilateral, whole-hemiface facial weakness pattern without historical or examination features suggesting a secondary cause…

  • Management

    First step for classic Bell palsy: start oral prednisone 60 mg PO once daily for 5 days, then tapered by 10 mg per day over the next 5 days, as a 10-day course, begun within 72 hours of symptom…

  • Complications

    Corneal exposure keratopathy: incomplete eyelid closure without adequate protection can progress to corneal abrasion, ulceration, and, rarely, vision loss.

  • Prognosis

    Favorable overall prognosis for Bell palsy: 70% to 90% of patients achieve full recovery within weeks, though early prednisone improves the rate and completeness of recovery.

  • Prevention

    No established primary prevention for idiopathic Bell palsy: the precise trigger is not fully defined, so there is no proven strategy to prevent a first episode.

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