Dermatology· Topic 3.4 Disorders of hair, nails, and pilosebaceous units· 3.4.6

Infections of the hand

Hand infections range from paronychia and purulent abscess to limb-threatening necrotizing fasciitis, are diagnosed by anatomic pattern and bite or wound history, and are managed by prompt incision and drainage or debridement plus empiric antibiotics targeting staphylococci, streptococci, and bite-specific organisms.

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What this article covers

  • Overview

    Hand infections span a spectrum from a localized nail-fold infection to a limb- and life-threatening necrotizing process, and the anatomic pattern of presentation (nail fold, pulp space, flexor…

  • Epidemiology

    Purulent infections are typically staphylococcal: acute paronychia is most commonly caused by Staphylococcus aureus.

  • Risk factors

    Trauma or chronic maceration leading to an incompetent cuticle: the precipitating factor for paronychia; frequent hand immersion in water drives the chronic form.

  • Pathophysiology

    Paronychia is infection of the nail fold following trauma or maceration that breaches the cuticle, most often with Staphylococcus aureus in the acute form.

  • Clinical features

    Paronychia: tender, erythematous nail fold swelling, typically a single nail in the acute form; chronic paronychia is more insidious, involves multiple fingers, with missing or dystrophic cuticles and nail ridging.

  • Differential diagnosis

    Necrotizing fasciitis: pain out of proportion to exam, hemorrhagic bullae, and crepitus, unlike the more indolent course of simple cellulitis or an abscess.

  • Diagnosis

    Most localized hand infections (paronychia, felon, abscess, herpetic whitlow) are diagnosed clinically by anatomic pattern and appearance, without routine culture or imaging; necrotizing fasciitis is…

  • Management

    First, irrigate and assess every hand wound, characterizing extent, depth, and neurovascular involvement, and obtain surgical evaluation for debridement or foreign body removal, particularly for any…

  • Complications

    Flexor tenosynovitis progressing to tendon necrosis and permanent loss of digit function if drainage is delayed.

  • Prognosis

    Localized purulent infections resolve promptly with drainage and appropriate antibiotics in the great majority of patients.

  • Prevention

    Prompt irrigation with sterile normal saline and wound assessment for every hand bite or puncture wound, as soon as possible after injury.

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