Pulmonary Disease and Critical Care· Topic 16.6 Pleural disease· 16.6.6

Pneumothorax

Pneumothorax is air in the pleural space, occurring spontaneously (primary in structurally normal lungs, secondary in underlying lung disease) or from trauma or procedures. Management is driven by size and hemodynamic stability, ranging from observation to needle aspiration to tube thoracostomy.

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What this article covers

  • Overview

    Air in the pleural space: pneumothorax occurs when air enters the potential space between the visceral and parietal pleura, collapsing the underlying lung and disrupting the normal negative…

  • Epidemiology

    Sex and age skew for PSP: primary spontaneous pneumothorax occurs mainly in tall, thin young men without any recognized underlying lung disease.

  • Risk factors

    Smoking (PSP and SSP): the single most important modifiable risk factor for both primary and secondary spontaneous pneumothorax.

  • Pathophysiology

    Loss of the normal negative pleural pressure: the pleural space normally sits at subatmospheric pressure, keeping the lung expanded against its elastic recoil; entry of air abolishes this gradient and the lung collapses toward the hilum.

  • Clinical features

    Sudden-onset pleuritic chest pain and dyspnea: the hallmark presentation, typically abrupt in onset and often occurring at rest.

  • Differential diagnosis

    Tension pneumothorax: distinguished by hemodynamic compromise (hypotension, distended neck veins, tracheal deviation) rather than size alone; treated emergently, not with imaging first.

  • Diagnosis

    Confirmed by chest imaging showing a visceral pleural line with absent lung markings peripheral to it; size is graded by the distance from the lung margin to the chest wall at the hilum on chest…

  • Management

    First, determine hemodynamic stability. Cardiovascular compromise (hypotension, increasing breathlessness) of any size mandates immediate management as tension pneumothorax with emergent needle…

  • Complications

    Tension pneumothorax: progression to hemodynamically significant obstructive physiology, requiring immediate needle decompression; discussed fully in its own entity.

  • Prognosis

    Recurrence dominates the long-term outlook: PSP recurs in 23-50% of patients within 1-5 years, and SSP recurs in more than 50% of patients within 1-3 years, without a recurrence-prevention procedure.

  • Prevention

    Recurrence-prevention intervention is indicated after the second ipsilateral episode of PSP, and after the first episode of SSP, and is also reasonable after a first PSP episode in a high-risk occupation (diving, aviation).

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