Cardiovascular Disease· Topic 2.7 Myocardial disease· 2.7.9

Right heart failure

Right heart failure is inability of the right ventricle to maintain output at acceptable filling pressures, most often from left heart failure or pulmonary hypertension, and acutely from pulmonary embolism or right ventricular infarction. It causes systemic venous congestion, and management centers on the underlying cause, careful volume and afterload optimization, and preload-dependent support in acute disease.

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What this article covers

  • Overview

    Definition: right heart failure is the inability of the right ventricle to maintain adequate output at acceptable filling pressures, producing systemic venous congestion and, when severe, low output.

  • Epidemiology

    Left heart failure is the most common cause of chronic right heart failure.

  • Risk factors

    Left heart failure and left-sided valve disease.

  • Pathophysiology

    Pressure overload: pulmonary hypertension or embolism raises right ventricular afterload, and the thin-walled right ventricle dilates and fails.

  • Clinical features

    Systemic venous congestion: elevated jugular venous pressure, peripheral edema, ascites, and a tender, pulsatile liver.

  • Differential diagnosis

    Left heart failure: the leading cause, with pulmonary congestion and orthopnea preceding the right-sided signs (Heart failure).

  • Diagnosis

    Establish clinically with echocardiography showing right ventricular dysfunction and identify the cause: the diagnostic basis is systemic venous congestion with echocardiographic evidence of right…

  • Management

    First-line, treat the underlying cause, continued long term: optimize left heart failure therapy, treat pulmonary hypertension, and reperfuse or anticoagulate pulmonary embolism.

  • Complications

    Cardiorenal and cardiohepatic syndromes. Refractory ascites and edema.

  • Prognosis

    Determined by the underlying cause and right ventricular recovery.

  • Prevention

    Treat left heart disease and pulmonary hypertension to prevent right ventricular failure.

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