Dermatology· Topic 3.6 Skin and soft tissue infections· 3.6.15

Skin abscess

A skin abscess is a purulent, fluctuant collection within the dermis and subcutaneous fat, usually caused by Staphylococcus aureus including MRSA, whose primary treatment is incision and drainage, with antibiotics reserved as an adjunct by size and systemic signs.

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What this article covers

  • Overview

    Definition: a skin abscess is an erythematous, nodular, fluctuant, localized collection of pus within the dermis and subcutaneous fat, distinguishing it from Cellulitis, a nonpurulent, spreading infection with no drainable collection.

  • Epidemiology

    Common presentation: purulent skin infections including furuncles, carbuncles, and abscesses are a frequent cause of skin and soft tissue infection evaluation, particularly where community-associated MRSA is prevalent.

  • Risk factors

    Skin barrier disruption: trauma, shaving, injection drug use, or a pre-existing follicular or cystic lesion (for example a ruptured epidermal inclusion cyst) provides the nidus for a purulent collection.

  • Pathophysiology

    Follicular or cutaneous origin: infection typically begins in a hair follicle (folliculitis) and progresses to a walled-off collection of neutrophils and necrotic debris as Staphylococcus aureus proliferates locally.

  • Clinical features

    Fluctuant, tender, erythematous nodule: the hallmark finding; palpation reveals a soft, compressible center indicating an underlying purulent collection.

  • Differential diagnosis

    Cellulitis: spreading, poorly demarcated erythema without a discrete fluctuant or purulent component; abscess has a palpable, drainable collection.

  • Diagnosis

    Skin abscess is a clinical diagnosis, confirmed on inspection: the diagnosis is established by the finding of a fluctuant, tender, purulent collection on physical exam; two or more inflammatory signs…

  • Management

    First, perform incision and drainage: this is the primary treatment for abscesses, furuncles, and carbuncles regardless of size; make an adequate incision at the point of maximal fluctuance, break up…

  • Complications

    Progression to cellulitis or lymphangitis: untreated or inadequately drained abscess can spread to surrounding tissue.

  • Prognosis

    Excellent with adequate incision and drainage: most localized abscesses, furuncles, and even carbuncles resolve fully once source control is achieved.

  • Prevention

    Hygiene measures for recurrent purulent infection: daily chlorhexidine washes and regular handwashing reduce recurrent MRSA transmission.

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