Nephrology and Urology· Topic 9.8 Male genital and sexual disorders· 9.8.4

Spermatocele

Spermatocele is a benign, sperm-containing cystic dilation of the epididymal duct or rete testis, palpated as a painless, mobile, fluctuant paratesticular nodule that transilluminates and appears as an anechoic extratesticular lesion on scrotal ultrasound; asymptomatic spermatoceles require no treatment, while large or painful ones are managed with surgical excision.

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What this article covers

  • Overview

    Definition: a spermatocele is a benign, sperm-containing cystic dilation of the epididymal duct or rete testis, arising as an outpouching from the epididymal tubule.

  • Epidemiology

    Common incidental finding on scrotal exam or ultrasound, frequently discovered during a routine physical, a fertility evaluation, or imaging obtained for an unrelated scrotal complaint.

  • Risk factors

    Prior epididymitis or epididymal inflammation, which can lead to focal tubular obstruction and cyst formation.

  • Pathophysiology

    Focal obstruction or dilation of the epididymal duct, or the efferent ductules of the rete testis, allows fluid and sperm to accumulate, forming a cystic outpouching proximal to the point of obstruction.

  • Clinical features

    A painless, mobile, fluctuant nodule palpated separate from and superior/posterior to the testis, most often at the head of the epididymis, is the hallmark finding.

  • Differential diagnosis

    Testicular tumor: a firm, non-tender, non-mobile, solid intratesticular mass that does not transilluminate, the diagnosis that must never be missed; ultrasound shows a hypoechoic intratesticular…

  • Diagnosis

    The diagnosis is established clinically by a painless, mobile, fluctuant paratesticular nodule that transilluminates on exam, with the testis itself palpating normally and separately from the mass…

  • Management

    First, confirm the mass is a simple, asymptomatic spermatocele on exam or ultrasound, since the large majority require no treatment beyond reassurance.

  • Complications

    Epididymal scarring and potential impairment of sperm transport after surgical excision, the main procedural risk that argues for observation whenever the spermatocele is asymptomatic.

  • Prognosis

    Excellent: spermatoceles are benign and do not undergo malignant transformation.

  • Prevention

    There is no established primary prevention for spermatocele, since the cause is degenerative ductal dilation rather than a modifiable exposure.

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