Neurology· Topic 10.4 Nerve root syndromes and mechanical lesions of the spine· 10.4.5

Lumbar spinal stenosis

Lumbar spinal stenosis is degenerative narrowing of the lumbar spinal canal that compresses the cauda equina and nerve roots, producing bilateral neurogenic claudication that worsens with standing and extension and improves with sitting or forward flexion, diagnosed clinically and confirmed by MRI, managed conservatively first with laminectomy reserved for refractory or progressive disease.

13 min read7 practice questions8 key factsSubscriber article
  • Topic review
    The full article, organized the way the exam asks it.
  • ABIM-format MCQs
    Vignettes with an explanation for every wrong answer.
  • Key facts
    The numbers and thresholds worth memorizing, up front.
  • AI tutor
    MedBrain answers the question you're stuck on.

What this article covers

  • Overview

    Degenerative narrowing of the lumbar spinal canal that compresses the cauda equina and traversing nerve roots: lumbar spinal stenosis is one of the most common identifiable causes of low back and leg…

  • Epidemiology

    One of the most common identifiable causes of low back and leg pain in older adults, alongside disc herniation and compression fracture; see low back pain.

  • Risk factors

    Increasing age, the dominant risk factor, reflecting cumulative facet, ligamentum flavum, and disc degeneration.

  • Pathophysiology

    Degenerative changes progressively narrow the canal, most commonly from facet osteoarthritic hypertrophy, ligamentum flavum thickening and buckling, and disc bulging, compressing the cauda equina and…

  • Clinical features

    Neurogenic claudication is the hallmark: bilateral (though often asymmetric) leg discomfort, numbness, tingling, or weakness provoked by standing and walking, absent when seated, and improved by…

  • Differential diagnosis

    Cauda equina syndrome: bowel/bladder dysfunction, saddle anesthesia, and decreased anal sphincter tone with a rapidly progressive bilateral deficit, unlike the chronic postural pattern of stenosis; a…

  • Diagnosis

    Lumbar spinal stenosis is a clinical diagnosis established by neurogenic claudication: bilateral leg pain worsened by standing and walking, absent when seated, and relieved by forward flexion, in an…

  • Management

    First, for mild to moderate symptoms, start an NSAID plus a structured program of abdominal and core muscle strengthening and weight loss when applicable, since core strengthening is specifically…

  • Complications

    Progressive neurogenic claudication limiting ambulation and function, the most common complication of untreated or undertreated stenosis, with substantial impact on independence in older adults.

  • Prognosis

    Often a slowly progressive degenerative condition, though the rate varies, and many remain stable for years with conservative management.

  • Prevention

    Maintain abdominal and core strengthening, specifically recommended for mild-to-moderate stenosis, to reduce symptom burden and delay progression to surgical candidacy.

Read the whole article

Subscribing to Internal Medicine opens every article, the full question bank and MedBrain, on the web, iPhone and Android.