Rheumatology and Orthopedics· Topic 17.2 Regional musculoskeletal syndromes· 17.2.6

Spondylosis

Spondylosis is degenerative osteoarthritis of the spine, with facet joint arthropathy and disk degeneration producing anterolateral osteophytes and disk-space narrowing on imaging, most consequential in the cervical spine where it can compress a nerve root (radiculopathy) or the spinal cord (myelopathy), diagnosed clinically and with MRI when neurologic compression is suspected, and managed conservatively unless myelopathy or progressive deficit develops.

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What this article covers

  • Overview

    Spondylosis is degenerative osteoarthritis of the spine, driven by facet joint arthropathy and disk degeneration, and radiographically defined by anterolateral spinous osteophytes with disk-space narrowing.

  • Epidemiology

    A common radiographic finding with advancing age, reflecting cumulative facet joint and disk degeneration analogous to osteoarthritis elsewhere in the body.

  • Risk factors

    Advancing age, the dominant risk factor, reflecting cumulative facet joint and intervertebral disk degeneration across decades.

  • Pathophysiology

    Disk degeneration reduces disk height and disk hydration, shifting mechanical load onto the posterior facet joints.

  • Clinical features

    Chronic axial neck or back pain worsened by extension and rotation and improved by rest, without radiation, in mechanical (non-compressive) spondylosis.

  • Differential diagnosis

    Compressive cervical myelopathy from another cause (tumor, epidural abscess, disk herniation): distinguished from spondylotic myelopathy by an acute or subacute course, fever, or a mass lesion on MRI…

  • Diagnosis

    Spondylosis is confirmed as the first step by plain radiographs showing anterolateral spinous osteophyte formation with disk-space narrowing; the separate and more urgent question, addressed next, is…

  • Management

    First, classify the presentation: mechanical pain only, radiculopathy, or myelopathy, since myelopathy and progressive deficits change the management pathway from conservative to surgical.

  • Complications

    Cervical spondylotic myelopathy: progressive cord compression can produce permanent gait, bladder, or bowel dysfunction if decompression is delayed.

  • Prognosis

    Mechanical (non-compressive) spondylosis generally has a favorable prognosis with conservative management, and most patients have resolution or near-resolution of symptoms within weeks to a few months.

  • Prevention

    Encourage regular range-of-motion and core/paraspinal strengthening exercise 2-3 times weekly to reduce symptomatic flares from age-related degenerative change, which is not itself modifiable.

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